Villains as PCs? Easy to do with FASERIP!
(Picture from a Marvel FASERIP game I ran at Gen Con 2015 - good times!)
First, my house-ruled Combat Cheat Sheet — with basically all the rules you need to play, as well as my own special-sauce tweaks and modifications — can be downloaded here.
Or, if your players don't like randomly rolling up new characters, check my very simple Point-Buy System for Marvel FASERIP right here.